| State: | TN |
| Type: | Sec |
| Route: | 365 |
| Map Custom: | yes |
| Map Notes: | TN 365 highlighted in red |
| Length Mi: | 3.7 |
| Established: | July 1, 1983[1] |
| Direction A: | South |
| Terminus A: | in Henderson |
| Junction: | in Henderson |
| Direction B: | North |
| Terminus B: | in Henderson |
| Counties: | Chester |
| Previous Type: | SR |
| Previous Route: | 364 |
| Next Type: | SR |
| Next Route: | 366 |
State Route 365 (SR 365) is a secondary north–south state highway located in Henderson, Chester County, Tennessee.
SR 365 begins at US 45 and SR 5. It then continues east through downtown Henderson as Main Street for approximately 0.8miles and turns in front of Freed-Hardeman University[2] onto White Avenue and continues for approximately 2.5miles ending between mile markers 7 and 8 of US 45.
Main Street at one time was part of SR 100 until the Noah Weaver Bypass was constructed which bypassed the downtown area. White Avenue was also once known as US 45 Business.[3]