| State: | TN |
| Type: | Sec |
| Route: | 288 |
| Map Custom: | yes |
| Map Notes: | SR 288 highlighted in red |
| Length Mi: | 17.6 |
| Established: | July 1, 1983[1] |
| Direction A: | South |
| Terminus A: | near McMinnville |
| Junction: | in Midway |
| Direction B: | North |
| Terminus B: | near Smithville |
| Counties: | Warren, DeKalb |
| Previous Type: | Sec |
| Previous Route: | 287 |
| Next Type: | Sec |
| Next Route: | 289 |
State Route 288 (SR 288) is a 17.6adj=midNaNadj=mid north-south state highway in Warren and DeKalb counties of Middle Tennessee.
SR 288 begins in Warren County at an intersection with US 70S/SR 1 just east of McMinnville. It heads northeast along Old Rock Island Road, a former alignment of US 70S, for a short distance before turning northwest along Hennessee Bridge Road. The highway winds its way northwest through farmland for several miles, where it crosses a bridge over the Collins River, to merge onto Francis Ferry Road and pass through Midway, where it has an intersection with SR 287.[2] SR 288 crosses into DeKalb County and winds its way through hillier terrain as Belk Road to pass through Antioch, where it becomes Antioch Road. It continues northwest to pass through Keltonburg, where it turns onto Keltonburg Road and crosses a bridge over a creek, before the highway turns completely west through flatter farmland for several miles before SR 288 comes to an end at an intersection with SR 56 just south of Smithville.[3] The entire route of SR 288 is a rural two-lane highway.