| Tenmile Creek | |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | New York |
| Subdivision Type3: | County |
| Subdivision Name3: | Albany |
| Subdivision Type4: | Towns |
| Subdivision Name4: | Rensselaerville |
| Subdivision Type5: | Villages |
| Subdivision Name5: | Medusa |
| Source1: | Myosotis Lake |
| Source1 Location: | Myosotis Lake, Village of Rensselaerville |
| Source1 Coordinates: | 42.5188°N -74.1452°W |
| Mouth: | Catskill Creek |
| Mouth Location: | Oak Hill, New York |
| Mouth Coordinates: | 42.4037°N -74.1352°W |
| Mouth Elevation: | 0feet |
Tenmile Creek is a 15adj=midNaNadj=mid[1] tributary of Catskill Creek in Albany County, New York. Via Catskill Creek, it is part of the Hudson River watershed.
Tenmile Creek runs through the villages of Rensselaerville and Medusa in the town of Rensselaerville. It approaches the village through a deep ravine, falling in the course of 0.6miles, which afforded great hydraulic power to early settlers.[2] The mill house in Medusa stood until the 1980s, when it was destroyed by fire.