Tayyaba Hasan Explained

Tayyaba Hasan
Workplaces:University of Pennsylvania
Harvard Medical School
Massachusetts General Hospital
Alma Mater:University of Karachi
University of Islamabad
University of Arkansas
Field:Dermatology
Photodynamic therapy
Known For:Visudyne

Tayyaba Hasan is a Professor of Dermatology at the Wellman Center for Photomedicine at Harvard Medical School. She is one of the inventors of Visudyne, a Food and Drug Administration approved treatment for age-related macular degeneration. She received the 2018 SPIE Britton Chance Biomedical Optics Award.

Early life and education

Hasan completed her bachelor's degree in chemistry at the University of Karachi in 1966.[1] She earned her master's degree in 1968, specialising in organic chemistry. In 1970 Hasan gained a second master's degree from the University of Islamabad. She won the National Merit Scholarship from the Punjab Education Foundation. She moved to the University of Arkansas for her postgraduate research, earning a PhD in organic chemistry in 1980.[2] She was elected to Sigma Xi.[3]

Research

After completing her PhD, Hasan joined the University of Pennsylvania as a postdoctoral research associate. She joined Harvard Medical School in 1982.[4] Hasan worked with Alan Oseroff on antibody conjugate photosensitization of cells for receptor-based photolysis.[5] She showed it was possible to target sub-cellular structures by photosensitisation.[6] Hasan uses photodynamic therapy to diagnose and treat disease.[7] She has trained dermatologists, ophthalmologists, urologists, gynaecologists and orthopaedic surgeons.

She demonstrated that benzoporphryin derivatives could be used to eliminate of subretinal vessels. She went on to discover visudyne with Ursula Schmidt. Visudyne is one of over twenty patents held by Hasan. She was appointed to professor of dermatology in 2009.[8] Her recent work considers ways to target glioma treatment and ovarian cancer. In 2011 she was the founding director of the Office for Research Career Development at Massachusetts General Hospital.[9] She is targeting diseases such as leishmaniasis, mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus. Hasan's lab focusses on the photophysical and biological mechanisms of photodynamic therapy. She leads a National Cancer Institute funded project focussed on image-guided therapy for pancreatic and skin cancers.[10] [11] These include singlet oxygen formation, cytokine secretion.

The Hasan Lab run several separate research projects:[12]

Hasan has served on the executive boards of several learned societies, including acting as President of the International Photodynamic Association, Vice President of Science for the Pan American PDT Association and President of the American Society for Photobiology (2010 - 2012).[17] She contributed to the 2014 book Photodynamic Therapy: From Theory to Application. She serves on the advisory board of Polythea.[18]

Awards

Notes and References

  1. Web site: Tayyaba Hasan on developments in photodynamic therapy.. spie.org. 2018-08-20.
  2. News: Fayetteville Northwest Arkansas Times Archives, Apr 11, 1979, p. 11. 1979-04-11. NewspaperArchive.com. 2018-08-20.
  3. Web site: Sigma Xi member directory. Sigma Xi. 2018-08-19.
  4. Book: Abdel-Kader, Mahmoud H.. Photodynamic Therapy: From Theory to Application. 2014-01-09. Springer Science & Business Media. 9783642396298.
  5. Pogue. Brian W.. Wagnières. Georges. Lilge. Lothar D.. September 2010. Special Section Guest Editorial: Pioneers in Biomedical Optics: Special Section Honoring Professor Tayyaba Hasan. Journal of Biomedical Optics. 15. 5. 051601–051601–2. 10.1117/1.3492580. 21054075. 1083-3668. 2010JBO....15e1601P. free.
  6. Shea. C. R.. Chen. N.. Wimberly. J.. Hasan. T.. 1989-07-15. Rhodamine dyes as potential agents for photochemotherapy of cancer in human bladder carcinoma cells. Cancer Research. 49. 14. 3961–3965. 0008-5472. 2736534.
  7. Web site: Tayyaba Hasan, Ph.D. – THE HASAN LABORATORY. hasanlab.mgh.harvard.edu. 2018-08-20.
  8. Web site: Tayyaba Hasan, PhD - DF/HCC. www.dfhcc.harvard.edu. 2018-08-20.
  9. Web site: Professor Tayyaba Hasan Receives IPA Award for Significant Advancement of Photodynamic Therapy. www.prnewswire.com. 2018-08-20.
  10. Web site: NCI Funded Research Portfolio - 1R01CA156177-01 Detail. fundedresearch.cancer.gov. 2018-08-20.
  11. Web site: NCI Funded Research Portfolio - 1UH2CA189901-01 Detail. fundedresearch.cancer.gov. 2018-08-20.
  12. Web site: THE HASAN LABORATORY – Photodynamic Therapy Research at Massachusetts General Hospital. hasanlab.mgh.harvard.edu. 2018-08-20.
  13. Web site: Project 1 Hasan Program. sites.dartmouth.edu. 2018-08-20.
  14. Web site: Project 2 & 5 Hasan Program. sites.dartmouth.edu. 2018-08-20.
  15. Web site: Project 3 Hasan Program. sites.dartmouth.edu. 2018-08-20.
  16. Web site: Project 4 Hasan Program. sites.dartmouth.edu. 2018-08-20.
  17. Book: 2016. Photodynamic Medicine. https://pubs.rsc.org/en/content/chapterhtml/2016/9781782626824-fp011?isbn=978-1-78262-682-4 . P011–P024. 10.1039/9781782626824-FP011. 2041-9724. 978-1-78262-451-6. Kostron. Herwig. Hasan. Tayyaba. Biographies. Comprehensive Series in Photochemical & Photobiological Sciences.
  18. News: Pr Tayyaba Hasan - Polythea. Polythea. 2018-08-20. fr-FR.
  19. Web site: 2019 Fellows of The Optical Society of America. 18 September 2019.
  20. Web site: ASP Spring 2018. 2018-08-22.
  21. Web site: Tayyaba Hasan honored with SPIE Britton Chance Biomedical Award. spie.org. 2018-08-20.
  22. News: Tayyaba Hasan, PhD, IPA President, honored with 2018 SPIE Britton Chance Biomedical Award. International Photodynamic Association (IPA). 2018-08-20.
  23. News: SAASCR Honors 8 Indian American Researchers for Contributions to Cancer Research. Reporter. India-West Staff. India West. 2018-08-20.
  24. Web site: Association . International Photodynamic . Professor Tayyaba Hasan Receives IPA Award for Significant Advancement of Photodynamic Therapy . 2022-03-06 . www.prnewswire.com . en.
  25. Web site: Professor Tayyaba Hasan Receives IPA Award for Significant Advancement of Photodynamic Therapy. 2018-08-22.
  26. Web site: Harvard Medical School Directors' Award for Service to HST community. 2018-08-22.
  27. Web site: 2018 NPA Garnett-Powers & Associates, Inc. Mentor Award Recipient Announced - National Postdoctoral Association. www.nationalpostdoc.org. 2018-08-20.
  28. Web site: The Wellman Center for Photomedicine: About Us: Leadership. wellman.massgeneral.org. 2018-08-20.
  29. News: William Silen Lifetime Achievement Excellence in Mentoring Awards Recipients. The Office for Diversity Inclusion and Community Partnership at Harvard Medical School. 2018-08-20.

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