Taxoid 7beta-hydroxylase explained

Taxoid 7beta-hydroxylase
Ec Number:	1.14.13.147

Taxoid 7beta-hydroxylase is an enzyme with systematic name taxusin,NADPH:oxygen 7-oxidoreductase.^[1] This enzyme catalyses the following chemical reaction

taxusin + O₂ + NADPH + H⁺

\rightleftharpoons

7beta-hydroxytaxusin + NADP⁺ + H₂O

Taxoid 7beta-hydroxylase requires cytochrome P450.

Notes and References

Chau M, Jennewein S, Walker K, Croteau R . Taxol biosynthesis: Molecular cloning and characterization of a cytochrome P450 taxoid 7 beta-hydroxylase . Chemistry & Biology . 11 . 5 . 663–72 . May 2004 . 15157877 . 10.1016/j.chembiol.2004.02.025 . free .