| Tawae-Siassi District | |
| Other Name: | Tewae-Siasi District |
| Pushpin Map: | Papua New Guinea |
| Coordinates: | -5.961°N 147.1943°W |
| Pushpin Label Position: | right |
| Pushpin Map Caption: | Location within Papua New Guinea |
| Subdivision Type: | Country |
| Subdivision Name: | Papua New Guinea |
| Subdivision Type1: | Province |
| Subdivision Name1: | Morobe Province |
| Seat Type: | Head Quarter |
| Seat: | Sialum |
| Area Total Km2: | 2535 |
| Population Total: | 54340 |
| Population As Of: | 2011 census |
| Population Density Km2: | auto |
| Demographics1 Title1: | Main languages |
| Leader Title: | MP |
| Leader Name: | Dr Kobby Bomareo |
| Timezone1: | AEST |
| Utc Offset1: | +10 |
Tewae-Siassi District (also spelled Tewae-Siasi District) is a district of the Morobe Province of Papua New Guinea. Its Head Quarter is Sialum. The population of the district was 54,340 at the 2011 census.[1]