Taurine—pyruvate aminotransferase explained

taurine-pyruvate aminotransferase
Ec Number:	2.6.1.77
Go Code:	0031299

In enzymology, a taurine-pyruvate aminotransferase is an enzyme that catalyzes the chemical reaction.

taurine + pyruvate

\rightleftharpoons L-alanine + 2-sulfoacetaldehyde

Thus, the two substrates of this enzyme are taurine and pyruvate, whereas its two products are L-alanine and 2-sulfoacetaldehyde.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is taurine:pyruvate aminotransferase. This enzyme is also called Tpa. This enzyme participates in taurine and hypotaurine metabolism.

References

• Laue H, Cook AM . 2000 . Biochemical and molecular characterization of taurine:pyruvate aminotransferase from the anaerobe Bilophila wadsworthia . Eur. J. Biochem. . 267 . 6841 - 8 . 11082195 . 10.1046/j.1432-1033.2000.01782.x . 23 . free .
• Cook AM, Denger K . 2002 . Dissimilation of the C2 sulfonates . Arch. Microbiol. . 179 . 1 - 6 . 12471498 . 10.1007/s00203-002-0497-0 . 1 . 19498355 .
• Masepohl B, Fuhrer F, Klipp W . 2001 . Genetic analysis of a Rhodobacter capsulatus gene region involved in utilization of taurine as a sulfur source . FEMS Microbiol. Lett. . 205 . 105 - 11 . 11728723 . 10.1111/j.1574-6968.2001.tb10932.x . 1 . free .