| Taquari-Guaçu River | |
| Name Other: | Taquari River |
| Source1 Location: | São Paulo state |
| Mouth: | Paranapanema River |
| Subdivision Type1: | Country |
| Subdivision Name1: | Brazil |
The Taquari-Guaçu or simply Taquari River is a river of São Paulo state in southeastern Brazil.