| Tangáxuan I | |
| Succession: | Cazonci of the Irechikwa Ts'intsuntsani |
| Reign: | (C.E.1435–1454) |
| Predecessor: | Hiripan |
| Successor: | Tzitzipandáquare |
Tangáxuan I was the fourth Cazonci of the Irechikwa Ts'intsuntsani in Mesoamerica, in what is now Mexico. He was the nephew of Tariácuri. His rule began around ~C.E.1435 and ended in 1454.