| Tamazulapam del Espíritu Santo | |
| Settlement Type: | municipality and town |
| Pushpin Label Position: | above |
| Pushpin Map Caption: | Location in Mexico |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Oaxaca |
| Population As Of: | 2005 |
| Timezone: | Central Standard Time |
| Utc Offset: | -6 |
| Timezone Dst: | Central Daylight Time |
| Utc Offset Dst: | -5 |
| Coordinates: | 17.05°N -100°W |
| Postal Code: | 951[1] |
| Area Code: | 70280[2] |
Tamazulapam del Espíritu Santo is a town and municipality in Oaxaca in south-western Mexico. The municipality is at an altitude of 2,040 meters.[3] It is part of the Sierra Mixe district within the Sierra Norte de Oaxaca Region.
The municipality has a total population of 6,908,[4] and the town has a population of 2,372.[5]
Municipal President Artemio Ortiz Ricardez died on May 13, 2020 during the COVID-19 pandemic in Mexico.[6] [7] The town had been placed under quarantine after its first reported case on May 10.[8]