| Official Name: | Talkhestan |
| Native Name: | تلخستان |
| Settlement Type: | village |
| Pushpin Map: | Iran |
| Mapsize: | 150px |
| Subdivision Type: | Country |
| Subdivision Type1: | Province |
| Subdivision Name1: | Markazi |
| Subdivision Type2: | County |
| Subdivision Name2: | Shazand |
| Subdivision Type3: | Bakhsh |
| Subdivision Name3: | Sarband |
| Subdivision Type4: | Rural District |
| Subdivision Name4: | Malmir |
| Population As Of: | 2006 |
| Population Total: | 183 |
| Population Density Km2: | auto |
| Timezone: | IRST |
| Utc Offset: | +3:30 |
| Timezone Dst: | IRDT |
| Utc Offset Dst: | +4:30 |
| Coordinates: | 33.785°N 48.9919°W |
Talkhestan (Persian: تلخستان, also Romanized as Talkhestān; also known as Qal‘eh Khān, Qal‘eh-ye Khān, Qal‘eh-ye Sharīf Khān, and Talkestān) is a village in Malmir Rural District, Sarband District, Shazand County, Markazi Province, Iran. At the 2006 census, its population was 183, in 51 families.