| Official Name: | Talkheh Dan-e Bozorg Amirabad |
| Native Name: | تلخه دان بزرگ اميراباد |
| Settlement Type: | village |
| Pushpin Map: | Iran |
| Mapsize: | 150px |
| Subdivision Type: | Country |
| Subdivision Type1: | Province |
| Subdivision Name1: | Kohgiluyeh and Boyer-Ahmad |
| Subdivision Type2: | County |
| Subdivision Name2: | Boyer-Ahmad |
| Subdivision Type3: | Bakhsh |
| Subdivision Name3: | Central |
| Subdivision Type4: | Rural District |
| Subdivision Name4: | Dasht-e Rum |
| Population As Of: | 2006 |
| Population Total: | 306 |
| Population Density Km2: | auto |
| Timezone: | IRST |
| Utc Offset: | +3:30 |
| Timezone Dst: | IRDT |
| Utc Offset Dst: | +4:30 |
| Coordinates: | 30.5742°N 51.4883°W |
Talkheh Dan-e Bozorg Amirabad (Persian: تلخه دان بزرگ اميراباد, also Romanized as Talkheh Dān-e Bozorg Amīrābād; also known as Talkh Dān) is a village in Dasht-e Rum Rural District, in the Central District of Boyer-Ahmad County, Kohgiluyeh and Boyer-Ahmad Province, Iran. At the 2006 census, its population was 306, in 57 families.