Talastine Explained

Talastine (trade name Ahanon) is an antihistamine.^[1]

Synthesis

The amide proton from 4-Benzylphalazone is abstracted with KOH, which is then alkylated with dimethylaminoethyl chloride.^{[2] [3]}

External links

• Web site: Talastine . .

Notes and References

1. Richter G, Kühn E . [Talastine (Ahanon) as a cause of allergic drug exanthema] . German . Dermatologische Monatschrift . 176 . 2–3 . 111–3 . 1990 . 1973126 .
2. DE . 1046625 . Engelbrecht, et al. . VEB Deutsches Hydrierwerk Rodleben . 1958 .
3. US . 3017411 . Engelbrecht, et al. . VEB Deutsches Hydrierwerk Rodleben . 1962 .