| Tacuarembó River | |
| Source1 Location: | near Rivera, Uruguay |
| Mouth Location: | Río Negro (Uruguay) |
| Subdivision Type1: | Country |
| Subdivision Name1: | Uruguay |
| Length: | 260km (160miles) |
The Tacuarembó River is a river in Uruguay. The Tacuarembó and the Yí Rivers are the principal tributaries of the Río Negro.
Among the tributaries of the Tacuarembó River are included the Caraguatá River.