| Official Name: | Tacotalpa |
| Settlement Type: | Municipal seat |
| Pushpin Map: | Mexico |
| Pushpin Map Caption: | Location in Mexico |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Tabasco |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | Tacotalpa |
| Established Title: | Founded |
| Unit Pref: | Metric |
| Population As Of: | 2010 |
| Population Total: | 8071 |
| Timezone: | Central Standard Time |
| Utc Offset: | −6 |
| Timezone Dst: | Central Daylight Time |
| Utc Offset Dst: | −5 |
| Elevation M: | 900 |
| Postal Code: | 86890 |
Tacotalpa is a small town in the southern Mexican state of Tabasco, the seat of the municipality of the same name. The city is located about 100abbr=onNaNabbr=on miles south of the coast of the Gulf of Mexico, and about 50km (30miles) kilometers from the state capital Villahermosa, near the border with the state of Chiapas. Tacotalpa is located near the Usumacinta River. In 2010, the population of the town consisted of 8,071 inhabitants.
The city of Tacotalpa currently has a population of 7,710 inhabitants, being one of the two smallest municipal capitals in Tabasco. INEGI 2020
Its name comes from the Nahuatl word Taco-tlal-pan, which means "land of brambles or weeds ." During the colonial era, when it was declared the capital of the province of Tabasco in 1677, the mayor Diego de Loyola founded the town with the name of Tacotalpa de la Real Corona.