Tabtoxinine β-lactam explained

Tabtoxinine β-lactam is a monobactam antibiotic derived from tabtoxin. Unlike other β-lactam antibiotics, which inhibit penicillin-binding proteins, tabtoxinine β-lactam inhibits glutamine synthetase.[1]

Notes and References

  1. Thomas . M. D. . Langston-Unkefer . P. J. . Uchytil . T. F. . Durbin . R. D. . Inhibition of Glutamine Synthetase from Pea by Tabtoxinine-β-lactam . Plant Physiology . 71 . 4 . 912–915 . 1983 . 16662928 . 1066143 . 10.1104/pp.71.4.912.

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