This is a table of drugs that are secreted in the kidney.
Acid medication are, because of pH partition, secreted to a higher extent when urine is basic. In the same way, basic medications are secreted to a higher extent when urine is acidic.
| Medication | Location | Acid or base[1] | anion or cation[2] | Percentage excreted[3] |
|---|---|---|---|---|
| para-aminohippurate | proximal tubule[4] | Acid | anion | |
| furosemide | Acid | anion | 100-75 | |
| glucuronic acid-conjugates | Acid | |||
| glycine conjugates | Acid | |||
| indometacin | Acid | anion | ||
| methotrexate | Acid | 100-75 | ||
| penicillin | Acid | anion | 75-50 (benzylpenicillin) | |
| probenecid | Acid | anion | ||
| sulphate conjugates | Acid | |||
| thiazide diuretics | Acid | |||
| uric acid | Acid | |||
| amiloride | Base | cation | ||
| dopamine | Base | |||
| histamine | Base | |||
| mepacrine | Base | |||
| morphine | Base | cation | ||
| pethidine | Base | |||
| quaternary ammonium compounds | Base | |||
| quinine | Base | cation | ||
| 5-hydroxytryptamine (serotonin) | Base | |||
| triamterene | Base | |||
| gentamicin | 100-75 | |||
| atenolol | 100-75 | |||
| digoxin | 100-75 | |||
| cimetidine | cation | 75-50 | ||
| tetracycline | 75-50 (oxytetracycline) | |||
| neostigmine | 75-50 | |||
| propantheline | ~50 | |||
| tubocurarine | ~50 | |||
| acetazolamide | proximal tubule[5] | anion | ||
| chlorothiazide | anion | |||
| saccharin | anion | |||
| salicylate | anion | |||
| atropine | cation | |||
| NMN | cation | |||
| paraquat | cation | |||
| procainamide | cation | |||
| tetraethylammonium | cation | |||
| chlorpromazine | cation | |||