Mildew resistance locus o explained

Mildew locus o (MLO) is a plant-specific gene family. Specific members of the Mildew Locus O gene family act as powdery mildew susceptibility factors. Their inactivation, as the result of a loss-of-function mutation, gene knock-out, or knock-down, is associated with a peculiar form of resistance, referred to as mlo resistance.[1] [2] The mlo gene family is widely conserved across the plant kingdom with some members evolving as early as the first land plants.[3] Mlo proteins contain seven highly conserved transmembrane domains, as well as a calmodulin-binding domain.[1] TaMLO genes are the MLOs in bread wheat, Triticum aestivum.[4]

MLO genes in tomatoes

At least 17 MLO genes exist in tomatoes.[1] They have a protein length of between 270 and 591 amino acids.[1]

Notes and References

  1. Web site: Genome-wide analysis of the mildew resistance locus o (MLO) gene family in tomato (Solanum lycopersicum L.). Plant Omics Journal. 2020-10-19.
  2. Structure, evolution and functional inference on the Mildew Locus O (MLO) gene family in three cultivated Cucurbitaceae spp.. 2015 . BMC Genomics. 10.1186/s12864-015-2325-3 . Iovieno . Paolo . Andolfo . Giuseppe . Schiavulli . Adalgisa . Catalano . Domenico . Ricciardi . Luigi . Frusciante . Luigi . Ercolano . Maria Raffaella . Pavan . Stefano . 16 . 1112 . 26715041 . 4696115 . free .
  3. Kusch . Stefan . Pesch . Lina . Panstruga . Ralph . Comprehensive Phylogenetic Analysis Sheds Light on the Diversity and Origin of the MLO Family of Integral Membrane Proteins . Genome Biology and Evolution . 2016 . 8 . 3 . 878–895 . 10.1093/gbe/evw036 . 26893454 . 4824068 . 11 January 2021. free .
  4. Li . Shaoya . Zhang . Chen . Li . Jingying . Yan . Lei . Wang . Ning . Xia . Lanqin . Present and future prospects for wheat improvement through genome editing and advanced technologies . . CAS Center for Excellence in Molecular Plant Sciences + Chinese Society for Plant Biology (Cell Press) . 2 . 4 . 2021 . 2590-3462 . 10.1016/j.xplc.2021.100211 . 100211. 34327324 . 8299080 .

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