TUBGCP5 explained

Gamma-tubulin complex component 5 is a protein that in humans is encoded by the TUBGCP5 gene.^{[1] [2]} It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.

See also

• Tubulin
• TUBGCP2
• TUBGCP3
• TUBGCP4
• TUBGCP6

Further reading

• Bittel DC, Kibiryeva N, Butler MG . Expression of 4 genes between chromosome 15 breakpoints 1 and 2 and behavioral outcomes in Prader–Willi syndrome . Pediatrics . 118 . 4 . e1276–83 . 2006 . 16982806 . 10.1542/peds.2006-0424 . 5453799 .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Suzuki Y, Yamashita R, Shirota M, etal . Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. . Genome Res. . 14 . 9 . 1711–8 . 2004 . 15342556 . 10.1101/gr.2435604 . 515316 .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Chai JH, Locke DP, Greally JM, etal . Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons. . Am. J. Hum. Genet. . 73 . 4 . 898–925 . 2003 . 14508708 . 10.1086/378816 . 1180611 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Nagase T, Kikuno R, Ohara O . Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. . DNA Res. . 8 . 4 . 179–87 . 2002 . 11572484 . 10.1093/dnares/8.4.179 . free .

Notes and References

1. Murphy SM, Preble AM, Patel UK, O'Connell KL, Dias DP, Moritz M, Agard D, Stults JT, Stearns T . GCP5 and GCP6: two new members of the human gamma-tubulin complex . Mol Biol Cell . 12 . 11 . 3340–52 . Nov 2001 . 11694571 . 60259 . 10.1091/mbc.12.11.3340.
2. Web site: Entrez Gene: TUBGCP5 tubulin, gamma complex associated protein 5.