TUBGCP4 explained

Tubulin, gamma complex associated protein 4 is a protein in humans that is encoded by the TUBGCP4 gene.^[1] It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.

See also

• Tubulin
• TUBGCP2
• TUBGCP3
• TUBGCP5
• TUBGCP6

Further reading

• Hsu HL, Yeh NH . Dynamic changes of NuMA during the cell cycle and possible appearance of a truncated form of NuMA during apoptosis . Journal of Cell Science . 109 (Pt 2) . 2 . 277–88 . February 1996 . 10.1242/jcs.109.2.277 . 8838651 .
• Haren L, Merdes A . Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail domain that bundles and stabilizes microtubules . Journal of Cell Science . 115 . Pt 9 . 1815–24 . May 2002 . 10.1242/jcs.115.9.1815 . 11956313 .
• Murphy SM, Preble AM, Patel UK, O'Connell KL, Dias DP, Moritz M, Agard D, Stults JT, Stearns T . GCP5 and GCP6: two new members of the human gamma-tubulin complex . Molecular Biology of the Cell . 12 . 11 . 3340–52 . November 2001 . 11694571 . 60259 . 10.1091/mbc.12.11.3340 .
• Fava F, Raynaud-Messina B, Leung-Tack J, Mazzolini L, Li M, Guillemot JC, Cachot D, Tollon Y, Ferrara P, Wright M . Human 76p: A new member of the gamma-tubulin-associated protein family . The Journal of Cell Biology . 147 . 4 . 857–68 . November 1999 . 10562286 . 2156165 . 10.1083/jcb.147.4.857 .
• Takahashi M, Yamagiwa A, Nishimura T, Mukai H, Ono Y . Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex . Molecular Biology of the Cell . 13 . 9 . 3235–45 . September 2002 . 12221128 . 124155 . 10.1091/mbc.E02-02-0112 .

Notes and References

1. Web site: Entrez Gene: Tubulin, gamma complex associated protein 4 .