TUBGCP2 explained

Gamma-tubulin complex component 2 is a protein that in humans is encoded by the TUBGCP2 gene.^{[1] [2]} It is part of the gamma-tubulin complex, which is required for microtubule nucleation at the centrosome.

See also

• Tubulin
• TUBGCP3
• TUBGCP4
• TUBGCP5
• TUBGCP6

Further reading

• Rush J . Immunoaffinity profiling of tyrosine phosphorylation in cancer cells . Nat. Biotechnol. . 23 . 1 . 94–101 . 2005 . 15592455 . 10.1038/nbt1046 . vanc. Moritz A . Lee KA . 3 . Guo . Ailan . Goss . Valerie L . Spek . Erik J . Zhang . Hui . Zha . Xiang-Ming . Polakiewicz . Roberto D . 7200157 .
• Gerhard DS . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . vanc. Wagner L . Feingold EA . 3 . Shenmen . CM . Grouse . LH . Schuler . G . Klein . SL . Old . S . Rasooly . R .
• Hillman RT, Green RE, Brenner SE . An unappreciated role for RNA surveillance . Genome Biol. . 5 . 2 . R8 . 2005 . 14759258 . 10.1186/gb-2004-5-2-r8 . 395752 . free .
• Bouwmeester T . A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway . Nat. Cell Biol. . 6 . 2 . 97–105 . 2004 . 14743216 . 10.1038/ncb1086 . vanc. Bauch A . Ruffner H . 3 . Angrand . Pierre-Olivier . Bergamini . Giovanna . Croughton . Karen . Cruciat . Cristina . Eberhard . Dirk . Gagneur . Julien . 11683986 .
• Ota T . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . vanc. Suzuki Y . Nishikawa T . 3 . Otsuki . Tetsuji . Sugiyama . Tomoyasu . Irie . Ryotaro . Wakamatsu . Ai . Hayashi . Koji . Sato . Hiroyuki . free .
• Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . vanc. Feingold EA . Grouse LH . 3 . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD . 2002PNAS...9916899M . free .
• Takahashi M . Centrosomal Proteins CG-NAP and Kendrin Provide Microtubule Nucleation Sites by Anchoring γ-Tubulin Ring Complex . Mol. Biol. Cell . 13 . 9 . 3235–45 . 2003 . 12221128 . 10.1091/mbc.E02-02-0112 . 124155 . vanc. Yamagiwa A . Nishimura T . 3 . Mukai . H . Ono . Y .
• Murphy SM . GCP5 and GCP6: Two New Members of the Human γ-Tubulin Complex . Mol. Biol. Cell . 12 . 11 . 3340–52 . 2002 . 11694571 . 10.1091/mbc.12.11.3340. 60259 . vanc. Preble AM . Patel UK . 3 . O'Connell . KL . Dias . DP . Moritz . M . Agard . D . Stults . JT . Stearns . T .
• Suzuki Y . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 . vanc. Yoshitomo-Nakagawa K . Maruyama K . 3 . Suyama . Akira . Sugano . Sumio .
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Adams MD . Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence . Nature . 377 . 6547 Suppl . 3–174 . 1995 . 7566098 . vanc. Kerlavage AR . Fleischmann RD . 3 . Fuldner . RA . Bult . CJ . Lee . NH . Kirkness . EF . Weinstock . KG . Gocayne . JD .

Notes and References

1. Murphy SM, Urbani L, Stearns T . The Mammalian γ-Tubulin Complex Contains Homologues of the Yeast Spindle Pole Body Components Spc97p and Spc98p . J Cell Biol . 141 . 3 . 663–74 . Jun 1998 . 9566967 . 2132743 . 10.1083/jcb.141.3.663 .
2. Web site: Entrez Gene: TUBGCP2 tubulin, gamma complex associated protein 2.