TRNA pseudouridine65 synthase explained

tRNA pseudouridine65 synthase
Ec Number:5.4.99.26
Cas Number:430429-15-5

tRNA pseudouridine65 synthase (TruC, YqcB) is an enzyme with systematic name tRNA-uridine65 uracil mutase.[1] This enzyme catalyses the following chemical reaction

tRNA uridine65

\rightleftharpoons

tRNA pseudouridine65

TruC specifically modifies uridines at positions 65 in tRNA.

Notes and References

  1. Del Campo M, Kaya Y, Ofengand J . Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli . RNA . 7 . 11 . 1603–15 . November 2001 . 11720289 . 1370202 .