TRIP4 explained

Activating signal cointegrator 1 is a protein that in humans is encoded by the TRIP4 gene.^{[1] [2]}

Interactions

TRIP4 has been shown to interact with Nuclear receptor coactivator 1.^[3]

Further reading

• Rual JF, Venkatesan K, Hao T, etal . Towards a proteome-scale map of the human protein-protein interaction network. . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .
• Rush J, Moritz A, Lee KA, etal . Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. . Nat. Biotechnol. . 23 . 1 . 94–101 . 2005 . 15592455 . 10.1038/nbt1046 . 7200157 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Jung DJ, Sung HS, Goo YW, etal . Novel transcription coactivator complex containing activating signal cointegrator 1. . Mol. Cell. Biol. . 22 . 14 . 5203–11 . 2002 . 12077347 . 10.1128/MCB.22.14.5203-5211.2002 . 139772 .
• Lee SK, Anzick SL, Choi JE, etal . A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo. . J. Biol. Chem. . 274 . 48 . 34283–93 . 1999 . 10567404 . 10.1074/jbc.274.48.34283 . free .
• Kim HJ, Yi JY, Sung HS, etal . Activating signal cointegrator 1, a novel transcription coactivator of nuclear receptors, and its cytosolic localization under conditions of serum deprivation. . Mol. Cell. Biol. . 19 . 9 . 6323–32 . 1999 . 10454579 . 10.1128/mcb.19.9.6323. 84603 .

Notes and References

1. Lee JW, Choi HS, Gyuris J, Brent R, Moore DD . Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor . Mol Endocrinol . 9 . 2 . 243–54 . Jul 1995 . 10.1210/mend.9.2.7776974 . 7776974 . free .
2. Web site: Entrez Gene: TRIP4 thyroid hormone receptor interactor 4.
3. Kim HJ, Yi JY, Sung HS, Moore DD, Jhun BH, Lee YC, Lee JW . Activating signal cointegrator 1, a novel transcription coactivator of nuclear receptors, and its cytosolic localization under conditions of serum deprivation . Mol. Cell. Biol. . 19 . 9 . 6323–32 . 1999 . 10454579 . 84603 . 10.1128/mcb.19.9.6323.