TRIP10 explained

Cdc42-interacting protein 4 is a protein that in humans is encoded by the TRIP10 gene.^{[1] [2] [3] [4]}

Interactions

TRIP10 has been shown to interact with STAT3,^[5] Wiskott-Aldrich syndrome protein,^[6] Huntingtin,^[7] CDC42,^[6] AKAP9^[8] and RHOQ.^[9]

Further reading

• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Tian L, Nelson DL, Stewart DM . Cdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubules. . J. Biol. Chem. . 275 . 11 . 7854–61 . 2000 . 10713100 . 10.1074/jbc.275.11.7854 . free .
• Linder S, Hüfner K, Wintergerst U, Aepfelbacher M . Microtubule-dependent formation of podosomal adhesion structures in primary human macrophages. . J. Cell Sci. . 113 Pt 23 . 4165–76 . 2001 . 23 . 10.1242/jcs.113.23.4165 . 11069762 .
• Richnau N, Aspenström P . Rich, a rho GTPase-activating protein domain-containing protein involved in signaling by Cdc42 and Rac1. . J. Biol. Chem. . 276 . 37 . 35060–70 . 2001 . 11431473 . 10.1074/jbc.M103540200 . free .
• Yuan R, Fan S, Achary M, etal . Altered gene expression pattern in cultured human breast cancer cells treated with hepatocyte growth factor/scatter factor in the setting of DNA damage. . Cancer Res. . 61 . 21 . 8022–31 . 2001 . 11691828 .
• Wang L, Rudert WA, Grishin A, etal . Identification and genetic analysis of human and mouse activated Cdc42 interacting protein-4 isoforms. . Biochem. Biophys. Res. Commun. . 293 . 5 . 1426–30 . 2002 . 12054674 . 10.1016/S0006-291X(02)00398-4 .
• Chang L, Adams RD, Saltiel AR . The TC10-interacting protein CIP4/2 is required for insulin-stimulated Glut4 translocation in 3T3L1 adipocytes. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 20 . 12835–40 . 2002 . 12242347 . 10.1073/pnas.202495599 . 130546 . 2002PNAS...9912835C . free .
• Dombrosky-Ferlan P, Grishin A, Botelho RJ, etal . Felic (CIP4b), a novel binding partner with the Src kinase Lyn and Cdc42, localizes to the phagocytic cup. . Blood . 101 . 7 . 2804–9 . 2003 . 12456510 . 10.1182/blood-2002-03-0851 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Holbert S, Dedeoglu A, Humbert S, etal . Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease. . Proc. Natl. Acad. Sci. U.S.A. . 100 . 5 . 2712–7 . 2003 . 12604778 . 10.1073/pnas.0437967100 . 151406 . 2003PNAS..100.2712H . free .
• Katoh M, Katoh M . FNBP2 gene on human chromosome 1q32.1 encodes ARHGAP family protein with FCH, FBH, RhoGAP and SH3 domains. . Int. J. Mol. Med. . 11 . 6 . 791–7 . 2004 . 12736724 . 10.3892/ijmm.11.6.791.
• Morin F, Vannier B, Houdart F, etal . A proline-rich domain in the gamma subunit of phosphodiesterase 6 mediates interaction with SH3-containing proteins. . Mol. Vis. . 9 . 449–59 . 2003 . 14502124 .
• Larocca MC, Shanks RA, Tian L, etal . AKAP350 interaction with cdc42 interacting protein 4 at the Golgi apparatus. . Mol. Biol. Cell . 15 . 6 . 2771–81 . 2004 . 15047863 . 10.1091/mbc.E03-10-0757 . 420101 .
• Chung YH, Cho NH, Garcia MI, etal . Activation of Stat3 transcription factor by Herpesvirus saimiri STP-A oncoprotein. . J. Virol. . 78 . 12 . 6489–97 . 2004 . 15163742 . 10.1128/JVI.78.12.6489-6497.2004 . 416526 .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Yin X, Warner DR, Roberts EA, etal . Identification of novel CBP interacting proteins in embryonic orofacial tissue. . Biochem. Biophys. Res. Commun. . 329 . 3 . 1010–7 . 2005 . 15752756 . 10.1016/j.bbrc.2005.02.075 .

Notes and References

1. Lee JW, Choi HS, Gyuris J, Brent R, Moore DD . Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor . Mol Endocrinol . 9 . 2 . 243–54 . July 1995 . 10.1210/mend.9.2.7776974 . 7776974 . free .
2. Aspenstrom P . A Cdc42 target protein with homology to the non-kinase domain of FER has a potential role in regulating the actin cytoskeleton . Curr Biol . 7 . 7 . 479–87 . August 1997 . 9210375 . 10.1016/S0960-9822(06)00219-3 . 14268690 . free .
3. Tsuji E, Tsuji Y . Molecular cloning and chromosomal localization of human salt-tolerant protein . Genetica . 108 . 3 . 259–62 . April 2001 . 11294612 . 10.1023/A:1004132919896. 22725257 .
4. Web site: Entrez Gene: TRIP10 thyroid hormone receptor interactor 10.
5. Chung . Young-Hwa . Cho Nam-hyuk . Garcia Maria Ines . Lee Sun-Hwa . Feng Pinghui . Jung Jae U . June 2004 . Activation of Stat3 transcription factor by Herpesvirus saimiri STP-A oncoprotein . J. Virol. . 78 . 12 . 6489–97 . United States. 0022-538X. 15163742 . 10.1128/JVI.78.12.6489-6497.2004 . 416526 .
6. 10.1074/jbc.275.11.7854 . Tian . L . Nelson D L . Stewart D M . March 2000 . Cdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubules . J. Biol. Chem. . 275 . 11 . 7854–61 . UNITED STATES. 0021-9258. 10713100 . free .
7. Holbert . Sébastien . Dedeoglu Alpaslan . Humbert Sandrine . Saudou Frédéric . Ferrante Robert J . Néri Christian . March 2003 . Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease . . 100 . 5 . 2712–7 . United States. 0027-8424. 12604778 . 10.1073/pnas.0437967100 . 2003PNAS..100.2712H . 151406 . free .
8. Larocca . M Cecilia . Shanks Ryan A . Tian Lan . Nelson David L . Stewart Donn M . Goldenring James R . June 2004 . AKAP350 interaction with cdc42 interacting protein 4 at the Golgi apparatus . Mol. Biol. Cell . 15 . 6 . 2771–81 . United States. 1059-1524. 15047863 . 10.1091/mbc.E03-10-0757 . 420101 .
9. Chang . Louise . Adams Rachael D . Saltiel Alan R . October 2002 . The TC10-interacting protein CIP4/2 is required for insulin-stimulated Glut4 translocation in 3T3L1 adipocytes . . 99 . 20 . 12835–40 . United States. 0027-8424. 12242347 . 10.1073/pnas.202495599 . 2002PNAS...9912835C . 130546 . free .