TRIM62 explained

TRIM62, also called DEAR1 (for ductal epithelium–associated RING chromosome 1),[1] is a protein in the tripartite motif family. In human it is encoded by the gene TRIM62.[2] TRIM62 is involved in the morphogenesis of the mammary gland, and loss of TRIM62 gene expression in breast is associated with a higher risk of recurrence in early-onset breast cancer.[1]

Notes and References

  1. DEAR1 Is a Dominant Regulator of Acinar Morphogenesis and an Independent Predictor of Local Recurrence-Free Survival in Early-Onset Breast Cancer . Lott ST, Chen N, Chandler DS, Yang Q, Wang L, etal . PLOS Medicine. 2009. 6. e1000068. 10.1371/journal.pmed.1000068 . 19536326 . 5 . 2673042 . Minna . John D. . free .
  2. Web site: TRIM62 tripartite motif-containing 62 [Homo sapiens ] |accessdate=1 Jun 2009 |publisher=Entrez Gene ].

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