TRIM45 explained

tripartite motif containing 45, also known as TRIM45, is a human gene.^[1]

This gene encodes a member of the tripartite motif family. The encoded protein may function as a [transcriptional repressor of the [[mitogen-activated protein kinase]] pathway. Alternatively spliced transcript variants have been described.^[1]

Further reading

• Sardiello M, Cairo S, Fontanella B, Ballabio A, Meroni G . Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties . BMC Evolutionary Biology . 8 . 225 . 2008 . 1 . 18673550 . 2533329 . 10.1186/1471-2148-8-225 . 2008BMCEE...8..225S . free .
• Wang Y, Li Y, Qi X, Yuan W, Ai J, Zhu C, Cao L, Yang H, Liu F, Wu X, Liu M . TRIM45, a novel human RBCC/TRIM protein, inhibits transcriptional activities of ElK-1 and AP-1 . Biochemical and Biophysical Research Communications . 323 . 1 . 9–16 . Oct 2004 . 15351693 . 10.1016/j.bbrc.2004.08.048 .
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides . Gene . 138 . 1–2 . 171–4 . Jan 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . Oct 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .

Notes and References

1. Web site: Entrez Gene: tripartite motif containing 45. 2011-08-30.