TRAPPC3 explained

Trafficking protein particle complex subunit 3 is a protein that in humans is encoded by the TRAPPC3 gene.^{[1] [2]}

Further reading

• Yu W, Andersson B, Worley KC, etal . Large-Scale Concatenation cDNA Sequencing . Genome Res. . 7 . 4 . 353–8 . 1997 . 9110174 . 10.1101/gr.7.4.353. 139146 .
• Sacher M, Jiang Y, Barrowman J, etal . TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion . EMBO J. . 17 . 9 . 2494–503 . 1998 . 9564032 . 10.1093/emboj/17.9.2494 . 1170591 .
• Barrowman J, Sacher M, Ferro-Novick S . TRAPP stably associates with the Golgi and is required for vesicle docking . EMBO J. . 19 . 5 . 862–9 . 2000 . 10698928 . 10.1093/emboj/19.5.862 . 305626 .
• Gavin AC, Bösche M, Krause R, etal . Functional organization of the yeast proteome by systematic analysis of protein complexes . Nature . 415 . 6868 . 141–7 . 2002 . 11805826 . 10.1038/415141a . 2002Natur.415..141G . 4425555 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Kim YG, Sohn EJ, Seo J, etal . Crystal structure of bet3 reveals a novel mechanism for Golgi localization of tethering factor TRAPP . Nat. Struct. Mol. Biol. . 12 . 1 . 38–45 . 2005 . 15608655 . 10.1038/nsmb871 . 22597154 .
• Turnbull AP, Kümmel D, Prinz B, etal . Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization . EMBO J. . 24 . 5 . 875–84 . 2005 . 15692564 . 10.1038/sj.emboj.7600565 . 554119 .
• Loh E, Peter F, Subramaniam VN, Hong W . Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus . J. Cell Sci. . 118 . Pt 6 . 1209–22 . 2005 . 15728249 . 10.1242/jcs.01723 . 3092909 . free .
• Rual JF, Venkatesan K, Hao T, etal . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .
• Kim MS, Yi MJ, Lee KH, etal . Biochemical and crystallographic studies reveal a specific interaction between TRAPP subunits Trs33p and Bet3p . Traffic . 6 . 12 . 1183–95 . 2006 . 16262728 . 10.1111/j.1600-0854.2005.00352.x . 24273412 .
• Kümmel D, Müller JJ, Roske Y, etal . Structure of the Bet3-Tpc6B core of TRAPP: two Tpc6 paralogs form trimeric complexes with Bet3 and Mum2 . J. Mol. Biol. . 361 . 1 . 22–32 . 2006 . 16828797 . 10.1016/j.jmb.2006.06.012 .
• Yu S, Satoh A, Pypaert M, etal . mBet3p is required for homotypic COPII vesicle tethering in mammalian cells . J. Cell Biol. . 174 . 3 . 359–68 . 2006 . 16880271 . 10.1083/jcb.200603044 . 2064232 .
• Kümmel D, Heinemann U, Veit M . Unique self-palmitoylation activity of the transport protein particle component Bet3: A mechanism required for protein stability . Proc. Natl. Acad. Sci. U.S.A. . 103 . 34 . 12701–6 . 2006 . 16908848 . 10.1073/pnas.0603513103 . 1562543 . 2006PNAS..10312701K . free .

Notes and References

1. Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA . A "double adaptor" method for improved shotgun library construction . Anal Biochem . 236 . 1 . 107–13 . Jun 1996 . 8619474 . 10.1006/abio.1996.0138 .
2. Web site: Entrez Gene: TRAPPC3 trafficking protein particle complex 3.