TRAF3IP3 explained

TRAF3-interacting JNK-activating modulator is a protein that in humans is encoded by the TRAF3IP3 gene.^{[1] [2]}

Interactions

TRAF3IP3 has been shown to interact with STRN,^[3] MOBKL3,^[3] STK24^[3] and FAM40A.^[3]

Further reading

• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides . Gene . 138 . 1–2 . 171–4 . Jan 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . Oct 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Vasilescu J, Zweitzig DR, Denis NJ, Smith JC, Ethier M, Haines DS, Figeys D . The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells . Journal of Proteome Research . 6 . 1 . 298–305 . Jan 2007 . 17203973 . 10.1021/pr060438j . 10.1.1.401.4220 .
• Zhang C, Xie L, Cheng H, Wang Y . TRAF3 interacts with Smac/DIABLO and enhances the proapoptotic effect of Smac/DIABLO in cytoplasm . Acta Biochimica et Biophysica Sinica . 39 . 2 . 108–16 . Feb 2007 . 17277885 . 10.1111/j.1745-7270.2007.00259.x . 19440495 .
• Ma X, Wang X, Gao X, Wang L, Lu Y, Gao P, Deng W, Yu P, Ma J, Guo J, Cheng H, Zhang C, Shi T, Ma D . Identification of five human novel genes associated with cell proliferation by cell-based screening from an expressed cDNA ORF library . Life Sciences . 81 . 14 . 1141–51 . Sep 2007 . 17868742 . 10.1016/j.lfs.2007.08.006 .

Notes and References

1. Dadgostar H, Doyle SE, Shahangian A, Garcia DE, Cheng G . T3JAM, a novel protein that specifically interacts with TRAF3 and promotes the activation of JNK(1) . FEBS Letters . 553 . 3 . 403–7 . Oct 2003 . 14572659 . 10.1016/S0014-5793(03)01072-X . 8938949 . free .
2. Web site: Entrez Gene: TRAF3IP3 TRAF3 interacting protein 3.
3. Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC . A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein . Molecular & Cellular Proteomics . 8 . 1 . 157–71 . Jan 2009 . 18782753 . 2621004 . 10.1074/mcp.M800266-MCP200 . free .