TPM4 explained

Tropomyosin alpha-4 chain is a protein that in humans is encoded by the TPM4 gene.^{[1] [2]}

Further reading

• Rasmussen HH, van Damme J, Puype M, etal . Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. . Electrophoresis . 13 . 12 . 960–9 . 1993 . 1286667 . 10.1002/elps.11501301199 . 41855774 .
• MacLeod AR, Talbot K, Smillie LB, Houlker C . Characterization of a cDNA defining a gene family encoding TM30p1, a human fibroblast tropomyosin. . J. Mol. Biol. . 194 . 1 . 1–10 . 1987 . 3612796 . 10.1016/0022-2836(87)90710-8 .
• MacLeod AR, Houlker C, Reinach FC, etal . A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism. . Proc. Natl. Acad. Sci. U.S.A. . 82 . 23 . 7835–9 . 1986 . 3865200 . 10.1073/pnas.82.23.7835 . 390864 . free .
• Lawrence B, Perez-Atayde A, Hibbard MK, etal . TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors. . Am. J. Pathol. . 157 . 2 . 377–84 . 2000 . 10934142 . 10.1016/S0002-9440(10)64550-6. 1850130 .
• Meech SJ, McGavran L, Odom LF, etal . Unusual childhood extramedullary hematologic malignancy with natural killer cell properties that contains tropomyosin 4--anaplastic lymphoma kinase gene fusion . Blood . 98 . 4 . 1209–16 . 2001 . 11493472 . 10.1182/blood.V98.4.1209 . free .
• Yi J, Kloeker S, Jensen CC, etal . Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers . J. Biol. Chem. . 277 . 11 . 9580–9 . 2002 . 11782456 . 10.1074/jbc.M106922200 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Gevaert K, Goethals M, Martens L, etal . Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides . Nat. Biotechnol. . 21 . 5 . 566–9 . 2004 . 12665801 . 10.1038/nbt810 . 23783563 .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Lin KT, Lu RM, Tarn WY . The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo . Mol. Cell. Biol. . 24 . 20 . 9176–85 . 2004 . 15456888 . 10.1128/MCB.24.20.9176-9185.2004 . 517884 .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Bruneel A, Labas V, Mailloux A, etal . Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis . Proteomics . 5 . 15 . 3876–84 . 2006 . 16130169 . 10.1002/pmic.200401239 . 26007149 .
• Rual JF, Venkatesan K, Hao T, etal . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .

Notes and References

1. Wilton SD, Lim L, Dorosz SD, Gunn HC, Eyre HJ, Callen DF, Laing NG . Assignment of the human alpha-tropomyosin gene TPM4 to band 19p13.1 by fluorescence in situ hybridization . Cytogenet Cell Genet . 72 . 4 . 294–6 . Jul 1996 . 8641132 . 10.1159/000134206 .
2. Web site: Entrez Gene: TPM4 tropomyosin 4.