TOX2 explained

TOX high mobility group box family member 2
Hgncid:	16095
Symbol:	TOX2
Altsymbols:	C20orf100, GCX-1
Entrezgene:	84969
Omim:	611163
Refseq:	NM_001098796
Uniprot:	Q96NM4
Chromosome:	20
Arm:	q
Band:	13.12

TOX high mobility group box family member 2, also known as TOX2, is a human gene.^{[1] [2]}

The protein encoded by this gene is a member of a subfamily of transcription factors that also includes TOX, TOX3, and TOX4 that share almost identical HMG-box DNA-binding domains which function to modify chromatin structure.^[3]

Notes and References

1. Web site: Entrez Gene: TOX high mobility group box family member 2.
2. Kajitani T, Mizutani T, Yamada K, Yazawa T, Sekiguchi T, Yoshino M, Kawata H, Miyamoto K . Cloning and characterization of granulosa cell high-mobility group (HMG)-box protein-1, a novel HMG-box transcriptional regulator strongly expressed in rat ovarian granulosa cells . Endocrinology . 145 . 5 . 2307–18 . May 2004 . 14764631 . 10.1210/en.2003-1343 . 25037508 .
3. O'Flaherty E, Kaye J . TOX defines a conserved subfamily of HMG-box proteins . BMC Genomics . 4 . 13 . April 2003 . 1 . 12697058 . 155677 . 10.1186/1471-2164-4-13 . free .