TNS4 explained

Tensin-4 is a protein that in humans is encoded by the TNS4 gene.^{[1] [2] [3]}

Further reading

• Bonaldo MF, Lennon G, Soares MB . Normalization and subtraction: two approaches to facilitate gene discovery. . Genome Res. . 6 . 9 . 791–806 . 1997 . 8889548 . 10.1101/gr.6.9.791 . free .
• Dias Neto E, Correa RG, Verjovski-Almeida S, etal . Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. . Proc. Natl. Acad. Sci. U.S.A. . 97 . 7 . 3491–6 . 2000 . 10737800 . 10.1073/pnas.97.7.3491 . 16267 . 2000PNAS...97.3491D . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Sasaki H, Yukiue H, Kobayashi Y, etal . Cten mRNA expression is correlated with tumor progression in thymoma. . Tumour Biol. . 24 . 5 . 271–4 . 2004 . 15001839 . 10.1159/000076141 . 46751099 .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Wan D, Gong Y, Qin W, etal . Large-scale cDNA transfection screening for genes related to cancer development and progression. . Proc. Natl. Acad. Sci. U.S.A. . 101 . 44 . 15724–9 . 2004 . 15498874 . 10.1073/pnas.0404089101 . 524842 . 2004PNAS..10115724W . free .
• Benzinger A, Muster N, Koch HB, etal . Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer. . Mol. Cell. Proteomics . 4 . 6 . 785–95 . 2005 . 15778465 . 10.1074/mcp.M500021-MCP200 . free .
• Lo SS, Lo SH, Lo SH . Cleavage of cten by caspase-3 during apoptosis. . Oncogene . 24 . 26 . 4311–4 . 2005 . 15806167 . 10.1038/sj.onc.1208571 . free .
• Liao YC, Si L, deVere White RW, Lo SH . The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1. . J. Cell Biol. . 176 . 1 . 43–9 . 2007 . 17190795 . 10.1083/jcb.200608015 . 2063623 .
• Katz M, Amit I, Citri A, etal . A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration. . Nat. Cell Biol. . 9 . 8 . 961–9 . 2007 . 17643115 . 10.1038/ncb1622 . 27088360 .
• Mouneimne G, Brugge JS . Tensins: a new switch in cell migration. . Dev. Cell . 13 . 3 . 317–9 . 2007 . 17765673 . 10.1016/j.devcel.2007.08.010 . free .

Notes and References

1. Lo SH, Lo TB . Cten, a COOH-terminal tensin-like protein with prostate restricted expression, is down-regulated in prostate cancer . Cancer Res . 62 . 15 . 4217–21 . Aug 2002 . 12154022 .
2. Sasaki H, Moriyama S, Mizuno K, Yukiue H, Konishi A, Yano M, Kaji M, Fukai I, Kiriyama M, Yamakawa Y, Fujii Y . Cten mRNA expression was correlated with tumor progression in lung cancers . Lung Cancer . 40 . 2 . 151–5 . Apr 2003 . 12711115 . 10.1016/S0169-5002(03)00037-0 .
3. Web site: Entrez Gene: TNS4 tensin 4.