TEGT explained
Bax inhibitor 1 is a protein that in humans is encoded by the TMBIM6 gene.[1] [2] [3]
Further reading
- Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
- Hillier LD, Lennon G, Becker M, etal . Generation and analysis of 280,000 human expressed sequence tags . Genome Res. . 6 . 9 . 807–28 . 1997 . 8889549 . 10.1101/gr.6.9.807 . free .
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
- Cowling RT, Birnboim HC . Preliminary characterization of the protein encoded by human testis-enhanced gene transcript (TEGT) . Mol. Membr. Biol. . 15 . 4 . 177–87 . 1999 . 10087504 . 10.3109/09687689709044319 . free .
- Jean JC, Oakes SM, Joyce-Brady M . The Bax inhibitor-1 gene is differentially regulated in adult testis and developing lung by two alternative TATA-less promoters . Genomics . 57 . 2 . 201–8 . 1999 . 10198159 . 10.1006/geno.1999.5761 . free .
- Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
- Grzmil M, Thelen P, Hemmerlein B, etal . Bax inhibitor-1 is overexpressed in prostate cancer and its specific down-regulation by RNA interference leads to cell death in human prostate carcinoma cells . Am. J. Pathol. . 163 . 2 . 543–52 . 2003 . 12875974 . 10.1016/S0002-9440(10)63682-6. 1868227 .
- Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
- Kimura K, Wakamatsu A, Suzuki Y, etal . Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes . Genome Res. . 16 . 1 . 55–65 . 2006 . 16344560 . 10.1101/gr.4039406 . 1356129 .
- Tanaka R, Ishiyama T, Uchihara T, etal . Expression of the Bax inhibitor-1 gene in pulmonary adenocarcinoma . Cancer . 106 . 3 . 648–53 . 2006 . 16353209 . 10.1002/cncr.21639 . 1629852 .
- Lee GH, Kim HK, Chae SW, etal . Bax inhibitor-1 regulates endoplasmic reticulum stress-associated reactive oxygen species and heme oxygenase-1 expression . J. Biol. Chem. . 282 . 30 . 21618–28 . 2007 . 17526500 . 10.1074/jbc.M700053200 . free .
Notes and References
- Walter L, Marynen P, Szpirer J, Levan G, Gunther E . Identification of a novel conserved human gene, TEGT . Genomics . 28 . 2 . 301–4 . Feb 1996 . 8530040 . 10.1006/geno.1995.1145 .
- Xu Q, Reed JC . Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast . Mol Cell . 1 . 3 . 337–46 . Jul 1998 . 9660918 . 10.1016/S1097-2765(00)80034-9 . free .
- Web site: Entrez Gene: TEGT testis enhanced gene transcript (BAX inhibitor 1).