TM7SF2 explained

Delta(14)-sterol reductase is an enzyme that in humans is encoded by the TM7SF2 gene.^{[1] [2] [3]}

Further reading

• Bennati AM, Castelli M, Della Fazia MA, etal . Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis. . Biochim. Biophys. Acta . 1761 . 7 . 677–85 . 2006 . 16784888 . 10.1016/j.bbalip.2006.05.004 .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Prakash A, Kasbekar DP . Genes encoding chimeras of Neurospora crassa erg-3 and human TM7SF2 proteins fail to complement Neurospora and yeast sterol C-14 reductase mutants. . J. Biosci. . 27 . 2 . 105–12 . 2002 . 11937680 . 10.1007/BF02703766 . 38757194 .
• Roberti R, Bennati AM, Galli G, etal . Cloning and expression of sterol Delta 14-reductase from bovine liver. . Eur. J. Biochem. . 269 . 1 . 283–90 . 2002 . 11784322 . 10.1046/j.0014-2956.2001.02646.x . free .
• Holmer L, Pezhman A, Worman HJ . The human lamin B receptor/sterol reductase multigene family. . Genomics . 54 . 3 . 469–76 . 1999 . 9878250 . 10.1006/geno.1998.5615 . free .

Notes and References

1. Lemmens IH, Kas K, Merregaert J, Van de Ven WJ . Identification and molecular characterization of TM7SF2 in the FAUNA gene cluster on human chromosome 11q13 . Genomics . 49 . 3 . 437–42 . Aug 1998 . 9615229 . 10.1006/geno.1998.5296 .
2. Lemmens I, Merregaert J, Van de Ven WJ, Kas K, Zhang CX, Giraud S, Wautot V, Buisson N, De Witte K, Salandre J, Lenoir G, Calender A, Parente F, Quincey D, Courseaux A, Carle GF, Gaudray P, De Wit MJ, Lips CJ, Hoppener JW, Khodaei S, Grant AL, Weber G, Kytola S, Thakker RV. Construction of a 1.2-Mb sequence-ready contig of chromosome 11q13 encompassing the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1 . Genomics . 44 . 1 . 94–100 . Nov 1997 . 9286704 . 10.1006/geno.1997.4872 . etal.
3. Web site: Entrez Gene: TM7SF2 transmembrane 7 superfamily member 2.