TLX2 explained

T-cell leukemia homeobox protein 2 is a protein that in humans is encoded by the TLX2 gene.^{[1] [2]}

Interactions

TLX2 has been shown to interact with YWHAH.^[3]

Further reading

• Kaifi JT, Wagner M, Schurr PG, Wachowiak R, Reichelt U, Yekebas EF, Mann O, Vashist Y, Kleinhans H, Link BC, Strate T, Kalinin V, Izbicki JR . Allelic loss of Hox11L1 gene locus predicts outcome of gastrointestinal stromal tumors . Oncology Reports . 16 . 4 . 915–9 . October 2006 . 16969514 . 10.3892/or.16.4.915 . free .
• Borghini S, Bachetti T, Fava M, Di Duca M, Cargnin F, Fornasari D, Ravazzolo R, Ceccherini I . The TLX2 homeobox gene is a transcriptional target of PHOX2B in neural-crest-derived cells . The Biochemical Journal . 395 . 2 . 355–61 . April 2006 . 16402914 . 1422762 . 10.1042/BJ20051386 .
• Parisi MA, Lipman NS, Clarke CM, Taylor B, Kapur RP . Evaluation of Hox11L1 in the fmc/fmc rat model of chronic intestinal pseudo-obstruction . Journal of Pediatric Surgery . 40 . 11 . 1760–5 . November 2005 . 16291166 . 10.1016/j.jpedsurg.2005.07.010 .
• Iitsuka Y, Shimizu H, Kang MM, Sasagawa K, Sekiya S, Tokuhisa T, Hatano M . An enhancer element for expression of the Ncx (Enx, Hox11L1) gene in neural crest-derived cells . The Journal of Biological Chemistry . 274 . 34 . 24401–7 . August 1999 . 10446220 . 10.1074/jbc.274.34.24401 . free .
• Tang SJ, Suen TC, McInnes RR, Buchwald M . Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins . The Journal of Biological Chemistry . 273 . 39 . 25356–63 . September 1998 . 9738002 . 10.1074/jbc.273.39.25356 . free .

Notes and References

1. Puliti A, Cinti R, Betsos N, Romeo G, Ceccherini I . HOX11L1, a gene involved in peripheral nervous system development, maps to human chromosome 2p13.1→p12 and mouse chromosome 6C3-D1 . Cytogenetics and Cell Genetics . 84 . 1–2 . 115–7 . Jun 1999 . 10343123 . 10.1159/000015234 . 21498122 .
2. Web site: Entrez Gene: TLX2 T-cell leukemia homeobox 2.
3. Tang SJ, Suen TC, McInnes RR, Buchwald M . Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins . The Journal of Biological Chemistry . 273 . 39 . 25356–63 . September 1998 . 9738002 . 10.1074/jbc.273.39.25356 . free .