TJP3 explained

Tight junction protein ZO-3 is a protein that in humans is encoded by the TJP3 gene.^[1]

Interactions

TJP3 has been shown to interact with tight junction protein 1.^[2]

Further reading

• Roh MH, Liu CJ, Laurinec S, Margolis B . The carboxyl terminus of zona occludens-3 binds and recruits a mammalian homologue of discs lost to tight junctions . The Journal of Biological Chemistry . 277 . 30 . 27501–9 . July 2002 . 12021270 . 10.1074/jbc.M201177200 . free .
• Kausalya PJ, Reichert M, Hunziker W . Connexin45 directly binds to ZO-1 and localizes to the tight junction region in epithelial MDCK cells . FEBS Letters . 505 . 1 . 92–6 . September 2001 . 11557048 . 10.1016/S0014-5793(01)02786-7 . 13489358 . free .
• Itoh M, Furuse M, Morita K, Kubota K, Saitou M, Tsukita S . Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins . The Journal of Cell Biology . 147 . 6 . 1351–63 . December 1999 . 10601346 . 2168087 . 10.1083/jcb.147.6.1351 .
• Wittchen ES, Haskins J, Stevenson BR . Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3 . The Journal of Biological Chemistry . 274 . 49 . 35179–85 . December 1999 . 10575001 . 10.1074/jbc.274.49.35179 . free .
• Haskins J, Gu L, Wittchen ES, Hibbard J, Stevenson BR . ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin . The Journal of Cell Biology . 141 . 1 . 199–208 . April 1998 . 9531559 . 2132714 . 10.1083/jcb.141.1.199 .

Notes and References

1. Web site: Entrez Gene: TJP3 tight junction protein 3 (zona occludens 3).
2. Wittchen ES, Haskins J, Stevenson BR . Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3 . The Journal of Biological Chemistry . 274 . 49 . 35179–85 . December 1999 . 10575001 . 10.1074/jbc.274.49.35179 . free .