TGM4 explained

Protein-glutamine gamma-glutamyltransferase 4 is an enzyme that in humans is encoded by the TGM4 gene.^{[1] [2] [3]}

Further reading

• Davies G, Ablin RJ, Mason MD, Jiang WG . Expression of the prostate transglutaminase (TGase-4) in prostate cancer cells and its impact on the invasiveness of prostate cancer. . J. Exp. Ther. Oncol. . 6 . 3 . 257–64 . 2007 . 17552366 .
• Kimura K, Wakamatsu A, Suzuki Y, etal . Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes . Genome Res. . 16 . 1 . 55–65 . 2006 . 16344560 . 10.1101/gr.4039406 . 1356129 .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Dubbink HJ, de Waal L, van Haperen R, etal . The human prostate-specific transglutaminase gene (TGM4): genomic organization, tissue-specific expression, and promoter characterization . Genomics . 51 . 3 . 434–44 . 1998 . 9721214 . 10.1006/geno.1998.5393 .
• Dubbink HJ, Verkaik NS, Faber PW, etal . Tissue specific and androgen-regulated expression of human prostate-specific transglutaminase . Biochem. J. . 315 (Pt 3) . Pt 3. 901–8 . 1996 . 8645175 . 10.1042/bj3150901. 1217292 .
• Amendola A, Lombardi G, Oliverio S, etal . HIV-1 gp120-dependent induction of apoptosis in antigen-specific human T cell clones is characterized by 'tissue' transglutaminase expression and prevented by cyclosporin A . FEBS Lett. . 339 . 3 . 258–64 . 1994 . 7906657 . 10.1016/0014-5793(94)80427-3 . 39872629 . free .
• Mariniello L, Esposito C, Di Pierro P, etal . Human-immunodeficiency-virus transmembrane glycoprotein gp41 is an amino acceptor and donor substrate for transglutaminase in vitro . Eur. J. Biochem. . 215 . 1 . 99–104 . 1993 . 7688299 . 10.1111/j.1432-1033.1993.tb18011.x . free .

Notes and References

1. Gentile V, Grant FJ, Porta R, Baldini A . Localization of the human prostate transglutaminase (type IV) gene (TGM4) to chromosome 3p21.33-p22 by fluorescence in situ hybridization . Genomics . 27 . 1 . 219–20 . Oct 1995 . 7665178 . 10.1006/geno.1995.1032 .
2. Grant FJ, Taylor DA, Sheppard PO, Mathewes SL, Lint W, Vanaja E, Bishop PD, O'Hara PJ . Molecular cloning and characterization of a novel transglutaminase cDNA from a human prostate cDNA library . Biochem Biophys Res Commun . 203 . 2 . 1117–23 . Oct 1994 . 7916568 . 10.1006/bbrc.1994.2298 .
3. Web site: Entrez Gene: TGM4 transglutaminase 4 (prostate).