TF-1 cell explained

TF-1 cells are immortal cell line derived from the human Erythroleukemia used in biomedical research.^[1] This cells are proliferatively responsive to interleukin-3 (IL-3) or granulocyte-macrophage colony-stimulating factor (GM-CSF).^[2] TF-1 cells have gene fusion of CBFA2T3-ABHD12.^[3]

See also

Other cell lines in LL-100 panel

External links

• Information on TF-1 in the ATCC catalog
• Cellosaurus entry for TF-1

Notes and References

1. Kitamura T, Tange T, Terasawa T, Chiba S, Kuwaki T, Miyagawa K, Piao YF, Miyazono K, Urabe A, Takaku F . Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin . . 1989 . 140 . 2 . 323–334 . 2663885 . 10.1002/jcp.1041400219. 44794601 .
2. Ihle JN, Askew D . Origins and properties of hematopoietic growth factor-dependent cell lines . . 1989 . 9 . 1 . 68–91 . 2656885 . 10.1002/stem.5530070202.
3. . 2019 . 9 . 1 . 101–11 . 10.1038/s41598-019-44491-x . free . The LL-100 panel: 100 cell lines for blood cancer studies . Quentmeier H, Pommerenke C, Dirks WG, Eberth S, Koeppel M, ((MacLeod RAF)), Nagel S, Steube K, Uphoff CC, Drexler HG . 31160637 . 6547646 . 2019NatSR...9.8218Q .