TEX11 explained
Testis expressed 11 is a protein that in humans is encoded by the TEX11 gene.[1]
Function
This gene is X-linked and is expressed in only male germ cells. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Further reading
- Wang PJ, McCarrey JR, Yang F, Page DC . An abundance of X-linked genes expressed in spermatogonia . Nat. Genet. . 27 . 4 . 422–6 . April 2001 . 11279525 . 10.1038/86927 . 14200121 .
- Aston KI, Krausz C, Laface I, Ruiz-Castané E, Carrell DT . Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent . Hum. Reprod. . 25 . 6 . 1383–97 . June 2010 . 20378615 . 10.1093/humrep/deq081 . free .
- Yatsenko AN, Georgiadis AP, Röpke A, Berman AJ, Jaffe T, Olszewska M, Westernströer B, Sanfilippo J, Kurpisz M, Rajkovic A, Yatsenko SA, Kliesch S, Schlatt S, Tüttelmann F . X-linked TEX11 mutations, meiotic arrest, and azoospermia in infertile men . N. Engl. J. Med. . 372 . 22 . 2097–107 . May 2015 . 25970010 . 4470617 . 10.1056/NEJMoa1406192 .
- Yang F, Silber S, Leu NA, Oates RD, Marszalek JD, Skaletsky H, Brown LG, Rozen S, Page DC, Wang PJ . TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse . EMBO Mol Med . 7 . 9 . 1198–210 . September 2015 . 26136358 . 4568952 . 10.15252/emmm.201404967 .
- Yang F, Silber S, Leu NA, Oates RD, Marszalek JD, Skaletsky H, Brown LG, Rozen S, Page DC, Wang PJ . TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse . EMBO Mol Med . 7 . 9 . 1198–210 . September 2015 . 26136358 . 4568952 . 10.15252/emmm.201404967 .
Notes and References
- Web site: Entrez Gene: Testis expressed 11. 2018-03-03.
