TB11Cs5H1 is a member of the H/ACA-like class of non-coding RNA (ncRNA) molecule that guide the sites of modification of uridines to pseudouridines of substrate RNAs. It is known as a small nucleolar RNA (snoRNA) thus named because of its cellular localization in the nucleolus of the eukaryotic cell. TB11Cs5H1 is predicted to guide the pseudouridylation of SSU ribosomal RNA (rRNA) at residue Ψ1710.[1]