TB10Cs1H2 snoRNA explained

TB10Cs1H2 is a member of the H/ACA-like class of non-coding RNA (ncRNA) molecule that guide the sites of modification of uridines to pseudouridines of substrate RNAs. It is known as a small nucleolar RNA (snoRNA) thus named because of its cellular localization in the nucleolus of the eukaryotic cell. TB10Cs1H2 is predicted to guide the pseudouridylation of LSU5 ribosomal RNA (rRNA) at residue Ψ901.[1]

Notes and References

  1. Liang XH, Uliel S, Hury A, Barth S, Doniger T, Unger R, Michaeli S . A genome-wide analysis of C/D and H/ACA-like small nucleolar RNAs in Trypanosoma brucei reveals a trypanosome-specific pattern of rRNA modification.. RNA. May 2005. 11. 5. 619–645. 15840815. 10.1261/rna.7174805. 1370750.

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