T1 holin family explained

The Phage T1 Holin (T1 Holin) Family (TC# 1.E.37) is represented in enterobacterial phages T1, RTP and F20, Klebsiella phage KP36, and Escherichia phage ADB-2. All of these possess a putative holin that share a high level of identity. Additionally, Gp9 of E. coli phage phiE49 is similar in sequence. These proteins are short, 55 to 71 amino acyl residues (aas) in length, and exhibit a single transmembrane segment (TMS).^[1] A representative list of proteins belonging to the T1 Holin family can be found in the Transporter Classification Database.^[2]

See also

• Holin
• Lysin
• Transporter Classification Database

Further reading

• 23856191 . 10.1016/j.bbamem.2013.07.004 . 3788059 . 1828 . Topological and phylogenetic analyses of bacterial holin families and superfamilies . 2013 . Biochim. Biophys. Acta . 2654–71 . Reddy . BL . Saier . MH. 11 . .
• 25157079 . 10.1128/JB.02046-14 . 197 . Holins in bacteria, eukaryotes, and archaea: multifunctional xenologues with potential biotechnological and biomedical applications . 4288690 . 2015 . J. Bacteriol. . 7–17 . Saier . MH . Reddy . BL. 1 . .
• 11018145 . 10.1146/annurev.micro.54.1.799 . 54 . Holins: the protein clocks of bacteriophage infections . 2000 . Annu. Rev. Microbiol. . 799–825 . Wang . IN . Smith . DL . Young . R. .
• 7669346 . 17 . Holins: form and function in bacteriophage lysis . 1995 . FEMS Microbiol. Rev. . 191–205 . Young . R . Bläsi . U . 1–2 . 10.1111/j.1574-6976.1995.tb00202.x. .

Notes and References

1. Catalão. Maria João. Gil. Filipa. Moniz-Pereira. José. São-José. Carlos. Pimentel. Madalena. 2013-07-01. Diversity in bacterial lysis systems: bacteriophages show the way. FEMS Microbiology Reviews. 37. 4. 554–571. 10.1111/1574-6976.12006. 1574-6976. 23043507. free.
2. Web site: The Phage T1 Holin (T1 Holin) Family. TCDB. 2016-03-28.