| Official Name: | Tłı̨chǫ Government |
| Native Name: | Tłı̨chǫ Ndekʼàowo (Tłı̨chǫ) |
| Native Name Lang: | dgr |
| Settlement Type: | Indigenous government |
| Motto: | Strong like two people |
| Mapsize: | 200 |
| Subdivision Type: | Country |
| Subdivision Name: | Canada |
| Subdivision Type1: | Territory |
| Subdivision Name1: | Northwest Territories |
| Subdivision Name2: | North Slave |
| Subdivision Type2: | Region |
| Subdivision Type3: | Territorial riding |
| Subdivision Name3: | Monfwi |
| Government Footnotes: | [1] |
| Leader Title: | Grand Chief |
| Leader Name: | Jackson Lafferty |
| Leader Title1: | Communities |
| Established Title: | Established |
| Established Date: | August 4, 2005 |
| Population Total: | 2751 |
| Population As Of: | 2016 |
| Postal Code Type: | Postal code |
| Root: | Tłı̨chǫ "dog-flank" |
| Person: | Tłı̨chǫ Done |
| People: | Tłı̨chǫ Done Do |
| Language: | Tłı̨chǫ Yatıì |
| Country: | Tłı̨chǫ Ndé, Denendeh |
The Tłı̨chǫ Government, or Tłı̨chǫ Ndekʼàowo (also rendered Tlicho Government and Tlicho Ndekʼaowo), is a First Nations organization representing the Tłı̨chǫ Nation, Dene people of the Northwest Territories, Canada, and covering much of their traditional territory, Tłı̨chǫ Ndé, within the larger Dene Country of Denendeh. The devolved government was created in 2005 when the Tłı̨chǫ Nation ratified the Tłı̨chǫ Agreement with the Government of Canada.
Through this agreement certain rights relating to lands, resources and self-government were defined including Tłı̨chǫ Government ownership of "39,000 km2 of land located between Lake Tıdeè and the Great Bear Lake including surface and subsurface rights, the ability to define its membership known as Tłı̨chǫ citizens, jurisdiction over lands and resources across Tłı̨chǫ Ndé and establishment of the Wekʼèezhìı Land and Water Board and the Wekʼèezhìı Renewable Resources Board and a share of mineral royalties from the Mackenzie Valley." The word Dogrib: Tlı̨chǫ pronounced as /[tɬʰĩtʃʰõ]/ means 'dog rib'.
The traditional area of the Tłı̨chǫ described by Chief Monfwi during the signing of Treaty 11 in 1921, was called Dogrib: Monfwı̀ Gogha Dè Nı̨htł'è pronounced as /[mõfwì goɣa dè nĩhtɬ'è]/. Wekʼèezhìi, the management area defined by the Tłı̨chǫ Agreement, is an area larger than the land owned by the Tłı̨chǫ. Wekʼèezhìi "shares boundaries with the Sahtu Settlement Area and Nunavut, and includes the four Tłı̨chǫ member communities of Gamèti, Wekweètì, Whatì and Behchokǫ̀." The area includes the Ekati and Diavik Diamond Mines.
The Tłı̨chǫ Government is one of the Management Authorities of the NWT Conference of Management Authorities (CMA) for boreal caribou, along with the Government of the NWT, the Wildlife Management Advisory Council (NWT), the Gwich'in Renewable Resources Board, the Sahtu Renewable Resources Board, and the Wekʼèezhìi Renewable Resources Board.
The Tłı̨chǫ Government appoints fifty percent of the Wekʼèezhìi Renewable Resource Board, a co-management board. The other fifty percent are appointed by the Government of Canada and the Government of Northwest Territory. The WRRB is an institution of public government, responsible for managing wildlife and wildlife habitat (forests, plants and protected areas) in the Wekʼèezhìi area.
Based on the 2012 Species at Risk Committee's (SARC) report, the NWT Conference of Management Authorities (CMA) in October 2013 added boreal woodland caribou to the Northwest Territories List of Species at Risk as a threatened species.