The 2007–08 Syrian Premier League is the 37th season of the Syrian Premier League, Syria's premier football league. It began on 27 September 2007.
Al-Wathba and Qardaha were relegated from the previous season.Afrin and Al-Nawair moved up from the Syrian League 1st Division.
| Club | City | Stadium | 2006-2007 season | |
|---|---|---|---|---|
| Al-Karamah | Homs | Khaled bin Walid Stadium | Syrian Premier League Champions | |
| Al-Ittihad | Aleppo | Aleppo International Stadium | 2nd in Syrian Premier League | |
| Al-Taliya | Hamah | Al Baladi Stadium | 3rd in Syrian Premier League | |
| Al-Majd | Damascus | Abbasiyyin Stadium | 4th in Syrian Premier League | |
| Al-Jaish | Damascus | Abbasiyyin Stadium | 5th in Syrian Premier League | |
| Teshrin | Latakia | Al Basil Stadium | 6th in Syrian Premier League | |
| Al-Futowa | Deir ez-Zor | Al Baladi Stadium | 7th in Syrian Premier League | |
| Al-Wahda | Damascus | Abbasiyyin Stadium | 8th in Syrian Premier League | |
| Hutteen | Latakia | Al Basil Stadium | 9th in Syrian Premier League | |
| Al-Shorta | Damascus | Abbasiyyin Stadium | 10th in Syrian Premier League | |
| Jableh | Jabala | Al-Baath Stadium | 11th in Syrian Premier League | |
| Al-Horriya | Aleppo | Aleppo International Stadium | 12th in Syrian Premier League | |
| Afrin | Afrin, Syria | Aleppo International Stadium | 2. Syrian League / North Champions | |
| Al-Nawair | Hamah | Al Baladi Stadium | 2. Syrian League / South Champions |
The top scorers from the Syrian Premier League 2007–08 are as follows:
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 |  Raja Rafe | Al-Majd | 21 |
| 2 | Ahmad Omaier | Al-Taliya | 14 |
| 3 | Mohamad Hamwi | Al-Karamah | 13 |
 Jésus Gomez | Al-Ittihad | ||
| Zakrea Semo Konda | Al-Jaish |