Syn-copalyl-diphosphate synthase explained

Syn-copalyl-diphosphate synthase
Ec Number:	5.5.1.14

Syn-copalyl-diphosphate synthase (OsCyc1, OsCPSsyn, syn-CPP synthase, syn-copalyl diphosphate synthase) is an enzyme with systematic name 9alpha-copalyl-diphosphate lyase (decyclizing).^{[1] [2]} This enzyme catalyses the following chemical reaction

geranylgeranyl diphosphate

\rightleftharpoons 9alpha-copalyl diphosphate

This enzyme requires a divalent metal ion, preferably Mg²⁺, for activity.

Notes and References

1. Otomo K, Kenmoku H, Oikawa H, König WA, Toshima H, Mitsuhashi W, Yamane H, Sassa T, Toyomasu T . Biological functions of ent- and syn-copalyl diphosphate synthases in rice: key enzymes for the branch point of gibberellin and phytoalexin biosynthesis . The Plant Journal . 39 . 6 . 886–93 . September 2004 . 15341631 . 10.1111/j.1365-313X.2004.02175.x . free .
2. Xu M, Hillwig ML, Prisic S, Coates RM, Peters RJ . Functional identification of rice syn-copalyl diphosphate synthase and its role in initiating biosynthesis of diterpenoid phytoalexin/allelopathic natural products . The Plant Journal . 39 . 3 . 309–18 . August 2004 . 15255861 . 10.1111/j.1365-313X.2004.02137.x . free .