| Sylvius Moore | |
| Birth Date: | 24 February 1912 |
| Birth Place: | Cape May, New Jersey, U.S. |
| Death Place: | Chicago, Illinois, U.S. |
| Player Years1: | 1931 |
| Player Team1: | Hampton |
| Coach Years1: | 1941–1942 |
| Coach Team1: | Phenix HS (VA) |
| Coach Years2: | 1943–1944 |
| Coach Team2: | Hampton |
| Overall Record: | 5–7–1 (college) |
Sylvius S. Moore Sr. (February 24, 1912 – September 10, 2004) was an American football player and coach.[1] He served as the head football coach at his alma mater, Hampton University in Hampton, Virginia, from 1943 to 1944, compiling a record of 5–7–1.[2]