| Official Name: | Sykes, Mississippi |
| Pushpin Map: | Mississippi#USA |
| Pushpin Label: | Sykes |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Mississippi |
| Subdivision Type2: | County |
| Subdivision Name2: | Clarke |
| Timezone: | Central (CST) |
| Utc Offset: | -6 |
| Timezone Dst: | CDT |
| Utc Offset Dst: | -5 |
| Elevation Ft: | 318 |
| Coordinates: | 32.0942°N -88.5922°W |
| Area Code: | 601 & 769 |
| Blank Name: | GNIS feature ID |
| Blank Info: | 692253 |
Sykes is an unincorporated community in Clarke County, Mississippi, United States. Sykes is located on Mississippi Highway 18 8.8miles east-northeast of Quitman.[1]
A post office operated under the name Sykes from 1903 to 1915.[2]