| Event: | Men's 50 metre backstroke S2 |
| Games: | 2012 Summer |
| Venue: | London Aquatics Centre |
| Dates: | 5 September |
| Competitors: | 10 |
| Nations: | 9 |
| Gold: | Yang Yang |
| Goldnpc: | CHN |
| Silver: | Aristeidis Makrodimitris |
| Silvernpc: | GRE |
| Bronze: | Dmitrii Kokarev |
| Bronzenpc: | RUS |
| Prev: | 2008 |
| Next: | 2016 |
The men's 50 metre backstroke S2 event at the 2012 Paralympic Games took place on 5 September, at the London Aquatics Centre.
Two heats were held, both with five swimmers. The swimmers with the eight fastest times advanced to the final.
| Rank | Lane | Name | Nationality | Time | Notes |
|---|---|---|---|---|---|
| 1 | 2 | Yang Yang | 1:01.35 | Q, WR | |
| 2 | 4 | Aristeidis Makrodimitris | 1:07.14 | Q | |
| 3 | 3 | Iad Josef Shalabi | 1:08.37 | Q | |
| 4 | 5 | Jacek Czech | 1:09.31 | Q | |
| 5 | 6 | Georgios Kapellakis | 1:11.80 | Q | |
| Rank | Lane | Name | Nationality | Time | Notes |
|---|---|---|---|---|---|
| 1 | 5 | James Anderson | 1:07.17 | Q | |
| 2 | 3 | Ievgen Panibratets | 1:07.33 | Q | |
| 3 | 4 | Dmitrii Kokarev | 1:10.93 | Q | |
| 4 | 6 | Francesco Bettella | 1:13.76 | ||
| 5 | 2 | Curtis Lovejoy | 1:16.06 | ||
| Rank | Lane | Name | Nationality | Time | Notes | |
|---|---|---|---|---|---|---|
| 4 | Yang Yang | 1:00.90 | WR | |||
| 5 | Aristeidis Makrodimitris | 1:04.71 | ||||
| 1 | Dmitrii Kokarev | 1:05.70 | ||||
| 4 | 3 | James Anderson | 1:07.30 | |||
| 5 | 7 | Jacek Czech | 1:07.74 | |||
| 6 | 2 | Iad Josef Shalabi | 1:08.97 | |||
| 7 | 8 | Georgios Kapellakis | 1:10.73 | |||
| 8 | 6 | Ievgen Panibratets | 1:11.03 |