| Event: | Men's 400m Freestyle S12 |
| Games: | 2012 Summer |
| Venue: | London Aquatics Centre |
| Dates: | 30 August |
| Competitors: | 11 |
| Nations: | 7 |
| Win Value: | 4:10.26 |
| Goldnpc: | RUS |
| Gold: | Sergey Punko |
| Silvernpc: | ESP |
| Silver: | Enrique Floriano |
| Bronzenpc: | UKR |
| Bronze: | Sergii Klippert |
The men's 400 metre freestyle S12 event at the 2012 Paralympic Games took place on 30 August, at the London Aquatics Centre.
Two heats were held, one with five swimmers and the other with six. The swimmers with the eight fastest times advanced to the final.
Sergey Punko won the gold medal in a time of 04:10.26. It was Russia's first gold of the London 2012 Paralympics.
| Rank | Lane | Name | Nationality | Time | Notes | |
|---|---|---|---|---|---|---|
| 1 | 4 | Enrique Floriano | 4:19.38 | Q | ||
| 2 | 2 | Sergii Klippert | 4:30.68 | Q | ||
| 3 | 6 | Ignacio Gonzalez | 4:33.33 | Q | ||
| 4 | 5 | Fabrizio Sottile | 4:38.09 | Q | ||
| 5 | 3 | Anton Stabrovskyy | 4:38.94 |
| Rank | Lane | Name | Nationality | Time | Notes | |
|---|---|---|---|---|---|---|
| 1 | 4 | Sergey Punko | 4:25.03 | Q | ||
| 2 | 5 | Tucker Dupree | 4:28.14 | Q | ||
| 3 | 3 | Omar Font | 4:30.13 | Q | ||
| 4 | 6 | Daniel Simon | 4:36.87 | Q | ||
| 5 | 2 | Jose Ramon Cantero Elvira | 4:40.45 | |||
| 6 | 7 | Oleg Tkalienko | 4:57.67 |
| Rank | Lane | Name | Nationality | Time | Notes | |
|---|---|---|---|---|---|---|
| 5 | Sergey Punko | 4:10.26 | ||||
| 4 | Enrique Floriano | 4:14.77 | ||||
| 2 | Sergii Klippert | 4:17.12 | ||||
| 4 | 6 | Omar Font | 4:21.01 | |||
| 5 | 3 | Tucker Dupree | 4:24.51 | |||
| 6 | 1 | Daniel Simon | 4:30.95 | |||
| 7 | 7 | Ignacio Gonzalez | 4:34.38 | |||
| 8 | 8 | Fabrizio Sotille | 4:36.74 |