See main article: article and Swimming at the 2010 South American Games. The Women's 1500m freestyle event at the 2010 South American Games was held on March 29 at 18:00.
| width=200 bgcolor=gold | Gold | width=200 bgcolor=silver | Silver | width=200 bgcolor=CC9966 | Bronze |
| Kristel Kobrich | Andreina Pinto | Yanel Pinto |
| Standing records prior to the 2010 South American Games | |||||
|---|---|---|---|---|---|
| World record | 15:42.54 | Mission Viejo, United States | 17 June 2007 | ||
| Competition Record | 16:30.55 | Buenos Aires, Argentina | 18 November 2006 | ||
| South American record | 15:57.57 | Rome, Italy | 28 July 2009 | ||
| Rank | Lane | width=250 | Athlete ! | width=100 | Result ! | Notes |
|---|---|---|---|---|---|---|
| 4 | 16:26.15 | CR | ||||
| 5 | 16:54.96 | |||||
| 5 | 17:17.21 | |||||
| 4 | 3 | 17:19.97 | ||||
| 5 | 2 | 17:53.41 | ||||
| 6 | 1 | 18:06.70 | ||||
| 7 | 7 | 18:19.67 | ||||
| 8 | 8 | 19:57.98 | ||||