See main article: article and Aquatics at the 2006 Commonwealth Games. The Women's 4 × 100 m Medley Relay at the 2006 Commonwealth Games occurred on Tuesday, 21 March 2006 at the Melbourne Sports and Aquatic Centre in Melbourne, Australia.[1] It was the second-to-last event of the swimming program at the Games, and the last women's event (the final event was the Men's 4x100 Medley Relay).
As 8 teams were entered in the event, it was only swum in finals.
Records at the start of the competition were:
| Place | Nation | Swimmers | Time | Notes |
|---|---|---|---|---|
| 1 | Sophie Edington (1:01.06) Leisel Jones (1:05.51) Jessicah Schipper (56.86) Lisbeth Lenton (52.87) | 3:56.30 | WR | |
| 2 | Melanie Marshall (1:01.64) Kate Haywood (1:08.54) Terri Dunning (59.40) Francesca Halsall (55.03) | 4:04.61 | ||
| 3 | Kelly Stefanyshyn (1:02.26) Lauren van Oosten (1:09.53) Audrey Lacroix (59.27) Erica Morningstar (54.89) | 4:05.95 | ||
| 4 | Hannah McLean (1:00.83) GR Annabelle Carey (1:09.73) Elizabeth Coster (1:00.06) Alison Fitch (55.68) | 4:06.30 | NR | |
| 5 | Melissa Corfe (1:03.39) Suzaan van Biljon (1:08.53) Mandy Loots (59.65) Lauren Roets (55.03) | 4:06.60 | ||
| 6 | Lorna Smith (1:05.54) Kirsty Balfour (1:08.11) Stephanie Hill (1:02.47) Caitlin McClatchey (55.88) | 4:12.00 | ||
| 7 | Hiang Yuet Ng (1:06.13) Joscelin Yeo (1:11.32) Li Tao (1:01.39) Mylene Ong (58.46) | 4:17.30 | ||
| 8 | Prabha Dharmadasa (1:17.47) Mayumi Raheem (1:21.00) Migali Gunatilake (1:16.62) Chathuri Abeykoon (1:08.56) | 5:03.65 | ||